Many people experience them, but talking about mental health problems remains taboo.

By the end of this year, one in four people are likely to be affected by a mental health condition. What can the arts do to open up a conversation about mental health? And how can they help the healing process? For example, can literature provide new ways of making sense of depression?

Speakers, writers, scientists and artists address major mental health issues head-on in Changing Minds.

Learn about how neuroscience is changing our understanding of what’s going on in our heads, explore the supposed link between madness and genius, and hear from the comedians who are laughing in the face of misunderstandings about mental health.

Saturday talks include:

10.30am – 11am Introducing Changing Minds

Speakers include Brian Dow, Director of External Affairs at Rethink Mental Illness; Sue Baker, Director of Time to Change; and Paul Farmer, CEO of Mind. Chaired by Jude Kelly, Artistic Director of Southbank Centre.

11.15am – 12pm Misunderstanding Mental Illness (BSL)

Though mental illness affects one in four people, stigma is often still attached to even the most common of conditions. Why do negative stereotypes of mental illness still persist, and what can we all do to paint a more sympathetic picture? A panel of service users, artists and activists discuss the many misunderstandings about mental illness. Featuring artist Stuart Semple, musician Jamie Baker, presenter and BBC journalist Attika Choudhary. Chaired by Dr Ike Anya.

This talk is British Sign Language-interpreted.

12.30pm – 1.30pm Arts vs. Chemicals (BSL)

We debate the pros and cons of medication in this panel discussion, featuring Dr David O'Flynn, consultant psychiatrist and chair of the Adamson Collection; Darryl Cunningham, cartoonist, illustrator and author of Psychiatric Tales; Rachel Kelly, journalist and author of Black Rainbow: How Words Healed Me; and Jo Marchant, author of Cure: A Journey Into the Science of Mind Over Body. Chaired by Tim Harrison, Director of Development at SICK! Festival.

This talk is British Sign Language-interpreted.

12.30pm – 1.30pm What's in Your Head?

Explore how the pioneering new area of neuroscience has unlocked our understanding of what's in our head. Poet Lavinia Greenlaw joins consultant neurologist Dr Suzanne O’Sullivan; Dr Dean Burnett, author of The Guardian's 'Brain Flapping' column and forthcoming book The Idiot Brain; and Academic Psychiatrist of the Year 2014, Dr Paola Dazzan.

2pm – 3pm Bites

Bites are mini talks featuring inspiring ideas, achievements, obsessions, stories, performances or manifestos and everything in between. This session features filmmaker Lotje Sodderland, who suffered a severe stroke at age 34 and made a Wellcome-funded award-winning documentary My Beautiful Broken Brain; Reveal, a rapper of Iranian decent who uses freestyling to delve into the subconscious; Chris Sav, illustrator and creator of the Disappointman series; and Priya Mistry, a theatre-maker who uses cabaret and variety to depict the symptoms caused by depression and anxiety.

2pm – 3pm Creativity of Sadness (BSL)

Theatre maker Cheryl Martin, cartoonist and graphic novelist Brick and writer, poet and performer Cecilia Knapp explore the role that sadness and deep depression can play in making art. This talk is chaired by Beth Elliot, director of Bethlem Gallery.

This talk is British Sign Language-interpreted.

3.30pm – 4.30pm What We Talk About When We Talk About Mental Health (BSL)

Is there a right or a wrong way to talk about mental health? From slang to clinical terms, there is no shortage of language to describe each condition. Performance artist Bobby Baker, The Guardian readers' editor Chris Elliott, author of The Man Who Couldn't Stop David Adam and Can I Start Again Please? performer Sue MacLaine discuss the language we use around mental health.

This talk is British Sign Language-interpreted.

3.30pm – 4.30pm Laughter's the Best Medicine

Mental illness is no joke – but for many, laughter is the best medicine. Meet the comedians who are laughing in the face of misunderstandings about mental health, for a discussion about how humour can take the sting out of stigma. Featuring comedians Jack Rooke and Sofie Hagen and poet and star of My Beautiful Black Dog Brigitte Aphrodite. Chaired by Heidi O’Loughlin.

5pm – 5.45pm Creative Therapy

Curated by Lambeth and Southwark Mind

What is the right type of therapy? How can therapists be creative in the consulting room? Therapists from different traditions will share insights into how they use imagination in their work. Chaired by Ajay Khandelwal, CEO of Lambeth and Southwark Mind, with Nicola Croote, Anouckha Grose, Priya Commander and Paul Gurney.

5pm – 5.45pm Rob Delaney in Conversation

Rob Delaney discusses depression and mental health with Andrew Hankinson, author of You Could Do Something Amazing With Your Life (You Are Raoul Moat). Following his critically acclaimed stand-up show Meat at Queen Elizabeth Hall and other national venues, the US comic – best known in the UK as the star and writer of Channel 4's hit comedy Catastrophe – returns to Southbank Centre. As well as having written for The Guardian and Vice, Rob's recent TV appearances include Have I Got News For You, 8 out of 10 Cats, The Graham Norton Show, Alan Carr: Chatty Man and Would I Lie to You?.